MYSP-PI-2022-063

张伟


下載導師簡歷CV
Section 1: Personal Particulars

张伟
zhang Wei
Associate Professor
+853 63869635
wzhang@must.edu.mo
I01-113, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau
Macau University of Science and Technology
MUST-SKL of Quality Research in Chinese Medicine
https://www.must.edu.mo/images/SKL/files/ZhangWei_TC_v180821.pdf

Research Project provided for Macao Youth Scholars Program:

融合多組學技術及質量標誌物理論開展川貝母等四種中藥的質量控制技術研究
Study on quality control of four Chinese herbal medicines through combining Q-marker theory and multi-omics technologies
1008 中药学
1007 药学
Postdoctoral training: Aug.2008-2012 Pharmacology Department, School of Medicine, Yale University, Ph.D. 2003- 2008, Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education) & Center for instrumental analysis, China Pharmaceutical University, Major: computational pharmaceutical analysis; Degree: Doctor of Science without passing Master period; B.A. 1996- 2000 College of pharmacy, China Pharmaceutical University, Major: Pharmaceutical analysis; Degree: Bachelor of Science.
Dr. Zhang’s research fields include phytochemical analysis of traditional Chinese medicines by modern instruments together with chemometric methods and the application of nanomaterials in analytical chemistry. His team has also discovered several nucleotide biomarkers and mechanism based combination therapy strategies for overcoming nucleotide analogs resistance for targeted therapies. He has published over 100 peer-reviewed SCI journals including Science Translational Medicine, Analytical Chemistry, Biochemical Pharmacology, Analyst, Analytical and Bioanalytical Chemistry, Analytica Chimica Acta, Talanta, Advanced Energy Materials and etc. Dr. Zhang obtained 6 Australia patents with the works related to the discovery of novel nucleotide biomarkers, novel nucleoside analogue enhancer for treatment of cancer and Non-alcoholic fatty liver disease.

Section 2: Research Interests and Grants

His research fields include the application of nanomaterials in analytical chemistry and energy storage, the use of chemometrics methods to deal with all steps of analytical procedures, phytochemical analysis.
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1. Integrative patterns of efficient components recognition of Aloe based on Wnt/β-Catenin signaling pathway, Macau Science and Technology Development Fund, MOP 1,112,100,2019-2022
2. Synergistic antitumor activity of 5-fluorouracil in colorectal cancer based on the targeted-regulation of nucleotide metabolism, Macau Science and Technology Development Fund, MOP 1,434,400,2019-2022
3. Study on multi-dimensional quality control of six Chinese herbal Medicines by combining artificial intelligence and multi-omics technologies,Macau Science and Technology Development Fund, MOP 8,000,000,2019-2022
4. Living single-cell analyzer based on light beam control and manipulation, 61827819, National Natural Science Foundation of China,RMB 7,769,000, 2019/1-2023/12