MYSP-PI-2022-025

林理根


下載導師簡歷CV
Section 1: Personal Particulars

林理根
Ligen Lin
Associate Professor
88228041
ligenl@um.edu.mo
Avenida da Universidade
University of Macau
UMAC-Institute of Chinese Medical Sciences
https://sklqrcm.um.edu.mo/li-gen-lin/

Research Project provided for Macao Youth Scholars Program:

脂肪細胞來源的外泌體對肝細胞脂肪動員的調節作用研究
The regulation of adipocyte derived exosomes on lipid mobilization in hepatocytes
1007 药学
0710 生物学
具有生物學或藥理學研究背景

Section 2: Research Interests and Grants

Natural products chemistry, development of new methods in isolation, structure elucidation, and target identification of bioactive natural products. Screening of novel lead compounds for treatment of obesity, diabetes and aging. Mechanism study for diet-related metabolic disorders.
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1. The deacetylase SIRT3 acts as a therapeutic target against nonalcoholic fatty liver disease through adipose tissue-liver axis, Ligen Lin, Macao Science and Technology Development Fund, 0031/2019/A1, MOP 2,316,400, 10/2019 – 9/2022.
2. The cyclic diarylheptanoid myricanol mitigates sarcopenia, its target identification, structural optimization, and mechanism studies, Ligen Lin, National Natural Science Foundation of China, 82073715, MOP 656,000, 01/2021 – 12/2024.