Section 1: Personal Particulars

Sookja Kim Chung
Macau University of Science and Technology
MUST-Faculty of Medicine
Member of Senate; Program Director

Research Project provided for Macao Youth Scholars Program:

Molecular mechanism of Caulerpa sulfated polysaccharides on immunometabolic reprogramming by targeting COX-2-induced ferroptosis
0710 生物学
1001 基础医学
Molecular biology; Omics; genetic engineering; animal models; stem cells
PhD or equivalent
Professor S. K. Chung is currently Professor at the Faculty of Medicine, Macau University of Science & Technology (M.U.S.T). She serve as a Hon. Professor to the School of Biomedical Sciences at The University of Hong Kong (HKU). She is also an Honorary Professor at the Air Force Military Medical University in Xian, China; Beijing Normal University-Hong Kong Baptist University, United International College in Zhuhai, China, and Chung-Nam Medical University in Daejeon, South Korea. She was a NIH Postdoctoral Fellow at the Northwestern Medical School and won the prestigious fellowship from Winston Foundation and worked at The Rockefeller University in New York, U.S.A. before moving to the Institute of Molecular Biology at HKU in 1991. Her research is notable for its powerful impact in several fields of medicine and science. The originality of her research is based on her great ability to generate and phenotype transgenic and knockout mice simulating a battery of human diseases. Her publications have appeared in top-tier journals, and she served as editorial board member and reviewers of numerous journals and grants. She delivered numerous invited lectures globally and served as a committee members of International Symposiums. She was also active in postgraduate teaching, and served as a member of Higher Degree Committee at HKU. Indicative of her great teaching acumen, students whom she has trained have won numerous awards and hold Professorships. Professor Chung has taught Histology at HKU for MBBS, TCM, Nursing, Biomedical Sciences, and Biomedical Engineering students for 28yrs. She was the coordinator for Histology practical at HKU. Currently, she teaches Histology combined with Pathology at the Medical Faculty of Macao University of Science & Technology. Awards: • Norman and Rosita Winston Fellowship (1988-1991), The Rockefeller University • Academic Scholarship (1974 - 1978), Lewis University • International Molecular Biology Network, elected member Patents and licensing: 1. Sookja Kim Chung, Stephen Chung and Chihiro Hibi, Preventive or therapeutic agent for cerebral ischemic injury or cerebral ischemia reperfusion in stroke, Filed on Aug 30, 2007, Patent No. 000144577 2. Sookja Kim Chung, Stephen Chung and Chihiro Hibi, Protective agent for retinal nerve or optic nerve, Patent Application 20100216856, 08/26/2010 3. Ip, Nancy Y, Ip, Fanny Chui Fun, Hu, Yueqing, Han, Yifan, Chung, Sookja Kim Heterodimers and methods of using them, United States Patent 7605265, Oct 20, 2009 4. Sookja Kim Chung, Stephen Chung and Chihiro Hibi, Protective agent for retinal nerve or optic nerve, European Patent Application, 13155114.5-1464, 23.04.13 5. Sookja Kim Chung and Philip So: 3D printing of microneedles: 201910278559.3 6. Licensing of aldose reductase-deficient Schwann cell line (IKARS1) in collaboration with Prof. Kazunori Sango, Japan to Applied Biological Materials Inc. (“Licensee”), with offices located at 1-3671 Viking Way Richmond, B.C.V6V 2J5 Canada. Total of 24 PRIZES AND AWARDS received by the supervised Postgraduate students and Postdoctoral Fellow as Primary Supervisor & 8 as co-supervisor

Section 2: Research Interests and Grants

RESEARCH FUNDING AS PRINCIPAL INVESTIGATOR: 1. S.K. Chung: Location of sorbitol dehydrogenase gene expression in mouse, CRCG, HK$ 60,000, July, 1992-1993, 35/089/0002 2. S.K. Chung and K.F. So: Molecular basis for regeneration of central nervous system: a possible regulatory role of growth associated protein-43, RGC, HK$ 486,000, 1993-1996, 338/089/0002 3. S.K. Chung: Tissue specific expression and developmental regulation of human endothelin-1 gene, CRCG, HK$ 72,000, July 1993-1996, 337/089/0001 4. S.K. Chung and S.S.M. Chung: Transgenic mouse models to study the molecular basis of diabetic neuropathy, RGC, HK$ 503,000, Sep 1994-Jun 1997, 338/089/0003 5. S.K. Chung: Characterization of endothelin-1 gene expressing transgenic lines, CRCG, HK$ 119,600, Jul 1994-1995, 335/089/0003 6. S.K. Chung: Study of the function of a developmentally essential gene, endothelin-1, using the two-tiered transgenic approach, RGC, HK$ 880,000, Aug 1995-1998, 338/089/0006 7. S.K. Chung: Structural organiz
4 co-supervised students
total of 75 students as PI (34) and Co-I (41)
FDCT-22-022-FMD 0007/2022/A 醛糖還原酶抑製劑依帕司他治療類風性濕關節炎的的藥效研究

871,600.00 01/09/2022 01/09/2024